Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum

Complementary and alternative medicine use by diabetes patients in Kerala, India See

The study assessed: (1) the prevalence of exclusive use of complementary and alternative medicine (CAM), exclusive use of modern medicine and combined use; (2) the factors associated with exclusive CAM use; and (3) the expenditure for CAM use among type-2 diabetes patients i...

Raman spectroscopy for the detection of organ distribution and clearance of PEGylated reduced graphene oxide and biological consequences See

Graphene, a 2D carbon material has found vast application in biomedical field because of its exciting physico-chemical properties. The large planar sheet like structure helps graphene to act as an effective carrier of drug or biomolecules in enormous amount. However, limited data availa...

Investigation of chronic toxicity of hydroxyapatite nanoparticles administered orally for one year in wistar rats See

Although the toxicity/biocompatibility of hydroxyapatite nanoparticles (nano HA), a prospective nano biomaterial is extensively studied, its interaction on biological systems following chronic exposure is less exploited. In the present study, Wistar rats were given various concentrations of nan...

Pattern, correlates and implications of non-communicable disease multimorbidity among older adults in selected Indian states: a cross-sectional study See

Objectives: The objective of the present study was to estimate the proportion of older adults with non-communicable disease (NCD) multimorbidity, its correlates and implications in selected Indian states. Methods: The study used data of 9852 older adults (≥60 years) (men&...

Enhancing an International Perspective in Public Health Teaching through Formalized University Partnerships See

Teaching in the field of public health needs to employ a global perspective to account for the fact that public health problems and solutions have global determinants and implications as well. International university partnerships can promote such a perspective through the ...

Metabolic Modulation by Medium-Chain Triglycerides Reduces Oxidative Stress and Ameliorates CD36-Mediated Cardiac Remodeling in Spontaneously Hypertensive Rat in the Initial and Established Stages of Hypertrophy See

Background: Left ventricular hypertrophy (LVH) is characterized by a decrease in oxidation of longchain fatty acids, possibly mediated by reduced expression of the cell-surface protein cluster of differentiation 36 (CD36). Spontaneously hypertensive rats (SHRs) were therefore supplemented with ...

Differential response of human cardiac stem cells and bone marrow mesenchymal stem cells to hypoxia-reoxygenation injury See

Cardiosphere-derived cells (CDCs) and bone marrow mesenchymal stem cells (MSCs) are popularly used in stem cell therapy for myocardial regeneration. The cell type that survives and maintains stem cell characteristics in the adverse microenvironment following ischemia–reperfusion injury&...

Octreotide-conjugated fluorescent PEGylated polymeric nanogel for theranostic applications See

Targeted nanocarriers can significantly increase the efficiency of therapeutic formulations by ensuring the site specific delivery of the cargo. Here in, we report a novel actively targeted fluorescent nanogel, PMB-OctN, based on photoluminescent comacromer [PEG-maleic acid-4 aminobenzoic acid...

Wound healing potential of scaffolds prepared from porcine jejunum and urinary bladder by a non-detergent/enzymatic method See

Scaffolds prepared using extracellular matrices of mammalian organs/tissues, when used as grafts, have wound healing potential. This paper evaluated the physical properties and invivo wound healing potential of jejunum-derived scaffold (JDS) and urinary bladder-derived scaffold (UDS) of porcine origin...

WHITHER INDIA MEDICAL LEGACY See

Women with epilepsy and infertility have different reproductive hormone profile than others See

Purpose: One-third of women with epilepsy (WWE) may experience infertility (failure to conceive after 12 months of regular unprotected intercourse). We aimed to compare the hormone profile of WWE and infertility (WWE-I) with that of WWE who had conceived earlier (WWE-F). Materials and&#...

Women's Autonomy and Its Correlates in Western Nepal: A Demographic Study See

Despite various efforts for enhancing women's autonomy in developing countries, many women are deprived of their capacity in decision -making on their household affairs as well as social issues. This paper aimed to examine women's autonomy and its associated factors in the Kapil...

Withdrawal of valproic acid treatment during pregnancy and seizure outcome: Observations from EURAP See

Based on data from the EURAP observational International registry of antiepileptic drugs (AEDs) and pregnancy, we assessed changes in seizure control and subsequent AED changes in women who underwent attempts to withdraw valproic acid (VPA) during the first trimester of pregnancy. Applying&#...

Wide to Narrow QRS Tachycardia: What Is the Mechanism? See

Women and Neuroscience Publishing: Is the Gender Gap closing in? See

WOMEN WITH EPILEPSY USING ANTI EPILEPTIC DRUGS HAVE LOW LEVELS OF ANTIOXIDANTS AND INCREASED OXIDATIVE STRESS See

WOMEN WITH EPILEPSY AND INFERTILITY HAVE ABNORMAL REPRODUCTIVE HORMONAL PROFILE See

What Does "Subclinical Rhythmic Electrographic Discharge of Adults" in EEG Signify? See

Subclinical rhythmic electrographic discharge of adults (SREDA) is the rarest benign epileptiform variant. It is an established EEG phenomenon that when present may cause confusion with an epileptic discharge for those unfamiliar with the entity. An electronic term search was performed on&#x...

Water soluble complexes of curcumin with cyclodextrins: Characterization by FT-Raman spectroscopy See

Many recent reports on curcumin, a polyphenol from Curcuma longa, provide mounting evidence on the pharmacological activity of this natural product. However, the pharmaceutical use of this molecule is hampered due to its poor solubility in the aqueous media. Inclusion complex formation ...