Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum

Strontium Hydroxyapatite scaffolds engineered with stem cells aid osteointegration and osteogenesis in osteoporotic sheep model. See

Osteoporotic fracture healing is an orthopaedic challenge due to excessive bone resorption and impaired osteogenesis. Majority of currenttreatment strategies focus on regulating bone resorption and the potential application of Mesenchymal Stem Cells (MSCs) in promoting osteogenesis has not been...

Low- level smoking among diabetes patients in India: a smoking cessation challenge See

Background: Little research in low and middle-income countries has been conducted on shifts in levels of smoking among those suffering from chronic diseases exposed to cessation messages. We present data on such shifts among diabetes patients participating in a randomized controlled&#...

Central lineassociated bloodstream infection: A study on creating awareness about specimen collection See

Background: Central line associated Blood stream infection(CLA-BSI) is a hospital acquired infection that is often missed. In a patient on a central line, culture of peripheral blood along with a sample of blood taken through the CL or CL tips is imperative, for a ...

Cultural adaptation of a peer-led lifestyle intervention program for diabetes prevention in India: the Kerala diabetes prevention program (K-DPP) See

Background: Type 2 diabetes mellitus (T2DM) is now one of the leading causes of disease-related deaths globally. India has the world’s second largest number of individuals living with diabetes. Lifestyle change has been proven to be an effective means by which to reduce ...

Degradation of Poly(-caprolactone) and bio-interactions with mouse bone marrow mesenchymal stem cells See

Bio-inspired scaffolds in bone tissue engineering using multipotential mesenchymal stem cells grow at a rapidrate foundits successfuluse inorthopedic injury treatment. Poly(-caprolactone)/PCL is widelyused in medical devices, tissue engineering, and drug delivery systems. Most desirable property of ...

Response of human cardiosphere derived cells to hypoxia-reoxygenation injury and its implications for myocardial regeneration See

Induced Pluripotent stem cells: Factors that determine Pluripotency See

Molecular Genetics of Von Willebrand Disease See

Interfacing of Nanographene with mouse bone marrow mesenchymal stem cells and its allied molecular toxicity using In vitro and In vivo methods See

Computational network modelling of excitatory and inhibitory responses in hippocampal Ca3 neurons See

Age-dependent variation in stem cell characteristics of the healthy and diseased heart See

Biomaterials Science: Studies on Polymer Nanogels for Theranostic Applications See

Biomaterials Science: Studies on Injectable Biomaterials for Cardiac Tissue Engineering See

Synthesis and evaluation of novel nanoprobes based on carbon dots for imaging and drug delivery applications See

Histamine 2 receptor antagonism for prevention of adverse cardiac remodelling in chronic pressure overload - A novel therapeutic strategy See

Biochemical and Molecular Basis for the Pro- atherogenic Property of Dysfunctional High Density Lipoprotein See

Gold nanorod decorated with cancer drug for multimodal imaging and therapy See

Cancer, a condition with uncontrolled cell division is the second leading cause of death worldwide. The currently available techniques for the imaging and treatment of cancer have their own limitations and hence a combination of more than one modality is expected to increase...

Blood brain barrier permeable gold nanocluster for targeted brain imaging and therapy: an in vitro and in vivo study. See

Blood brain barrier (BBB) is a dynamic interface, comprising polarized endothelial cells, that separates the brain from the circulatory system. The highly protective nature of this tight junction impairs diagnosis and treatment of brain disorders. In this study, we designed a sub...

Optical redox ratio using endogenous fluorescence to assess the metabolic changes associated with treatment response of bioconjugated gold nanoparticles in streptozotocin-induced diabetic rats See

Fluorescence spectroscopic techniques have the potential to assess the metabolic changes during disease development and evaluation of treatment response in a non-invasive and label-free manner. The present study aims to evaluate the effect of mulberry-mediated gold nanoparticles (MAuNPs) ...