Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum

Impact of left renal vein division during abdominal aortic aneurysm surgery on immediate and long-term renal function See

Open surgical repair is the gold standard in the treatment of abdominal aortic aneurysms. The surgical technique has improved so vastly over the years, that even high risk patients can undergo the procedure with acceptable morbidity. Juxtarenal aortic aneurysms and&...

Study of the predictors of rupture of a specific aneurysm in a patient diagnosed with multiple aneurysms - a prospective exploratory observational study See

Cerebral aneurysms rupture leads to subarachnoid hemorrhage which leads to significant morbidity and mortality. The outcome after subarachnoid hemorrhage due to aneurysmal rupture is still poor; mortality rates ranges from 40-50%, severe disability in 10-20% and only 40% ...

Prospective observational study of patients undergoing anterior petrosectomy See

The anterior petrous apex has been considered as a gateway to the posterior cranial fossa. The anterior petrosectomy as described by Kawase converts this deep narrow operative corridors into wider shallower exposures, improves manoeuvrability and minimizes retraction. It compr...

Prospective observational study for the evaluation of clinical and radiological correlates in patients undergoing surgery for vestibular schwannoma See

Cerebellopontine angle (CPA) tumours comprise 5 to 10 percent of all intracranial tumours. Around 90 % of all CPA tumours are vestibular schwannomas, which are benign tumours of the vestibular portion of the vestibulocochlear nerve, arising from the Schwann cells. They firs...

Prospective observational study of outcomes of different transcranial approaches for craniopharyngiomas See

Craniopharyngioma: “One would expect these congenital epithelial tumors to be capable of enucleation like Dermoid cysts elsewhere in the body, but they so definitely adhere to the adjacent structures neighboring on their place of origin, it is rarely possible to...

Study of haemodynamics of Chitra Valve in mitral position- a single centre experience See

In India, a large number of people suffer Rheumatic heart disease and related complications. It is estimated that six out of every 1000 children suffer Rheumatic fever between the age of five and fifteen years. The major cause of long term morbidity and �...

Prognostic indicators in guillain barre syndrome with special reference to serum albumin See

Guillain Barre syndrome (GBS) is a common cause of neuromuscular paralysis, the annual incidence of which is reported to be 0.81–1.89 per 100,000 person–years.1 It is characterised by the combination of rapidly progressive symmetrical weakness in the limbs with...

A clinical study on the utility of muscle biopsy in patients with suspected myopathy See

Myopathy is one of the common disorders in patients attending neuromuscular clinic. Systematic approach comprising a comprehensive clinical history, thorough neurological and systemic examination, nerve conduction studies, EMG and relevant biochemical tests should be undertaken in ...

Correlation between pulsatility index (pi) in transcranial doppler (tcd) and cognitive profile of patients with alzheimer’s dementia and vascular dementia See

The World Health Organization (WHO) predicts that by 2025, about 3/4th of the estimated 1.2 billion people aged >60 years will reside in developing countries1 . 4.6 million new cases of dementia are added every year, and the highest rate of growth i...

Disability adjusted life years as measure of burden of epilepsy in persons who undergo seizure monitoring See

ndia and other developing countries are undergoing a phase of epidemiological transition where in the burden of non-communicable diseases (NCD) is increasing. This transition is probably due to transformation of scenario with improving health care services in preventive ...

Sex differences in risk factor profile, clinical presentation, stroke subtype and outcome in acute ischemic stroke See

Stroke is currently the second leading cause of death worldwide. Ischemic heart disease and stroke together accounted for 15.2 million deaths (15–15.6 million) in 2015(1). Stroke is the commonest cause of chronic adult disability(2). Stroke affects 33 million individuals...

Comparison of two anaesthetic regimens TIVA (Propofol-fentanyl) versus Inhalation (Sevoflurane-fentanyl) on perioperative haemodynamic, operating conditions and immediate postoperative outcomes in patients undergoing elective neurosurgical procedures involving brain&... See

Neurosurgical procedures involving craniotomy and resection of brain tumors are usually carried out under general anaesthesia. The goals of anaesthesia during neurosurgical procedures are smooth induction, stable intra operative haemodynamics, providing optimal surgical condition, adequate brain re...

Evaluation of Cerebral Perfusion Pressure (CPP) and Cerebral blood flow (CBF) in different Head of Bed positions using Transcranial Doppler in Neurosurgical patients See

It is well known that optimal maintenance of cerebral hemodynamics is important to reduce the risk for secondary brain injury in neurosurgical patients. Acute Neurological illness like Traumatic brain injury, Subarachnoid haemorrhage, Intracerebral haemorrhage, Ischemic stroke, Meningit...

Comparison of Effects of Propofol and Dexmedetomidine on Motor Evoked Potentials in Neurosurgery: A Prospective Randomised Single Blinded Interventional Study See

Intraoperative neurophysiological monitoring (IONM) is often used in various intracranial and spine procedures to prevent damage to eloquent areas, cranial nerves or motor or sensory tracts. Motor evoked potential (MEP) monitoring is invariably an essential tool in the a...

Imaging of indirect carotid cavernous fistula comparing advanced mri sequences with digital subtraction angiography See

Carotid-cavernous fistulas (CCFs) are abnormal arteriovenous communications either directly between the internal carotid artery (ICA) and the cavernous sinus or between the dural branches of the internal and external carotid arteries. Several classification schemes have categorized...

Role of quantitative susceptibility weighted imaging in evaluating disease activity of lesions in multiple sclerosis See

Multiple sclerosis (MS) is an inflammatory demyelinating and neurodegenerative disease of the central nervous system. Majority of the patients start with a relapsing –remitting course, which has clearly defined episode of neurologic disability and recovery. Pathologic hallmark �...

Comparison of 3d rotational angiography with digital subtraction angiography and correlation of angioarchitecture with clinical presentations in cerebral arteriovenous malformations See

Brain arteriovenous malformations (AVM) are an intriguing disease entity involving the intracranial vasculature where arteries and veins are interconnected through a low resistance dysplastic nidus bypassing the normal intervening capillary network.[1] There are several morpholo...

Morphological abnormalities in hypertrophic cardiomyopathy - a cardiac mri based study See

Hypertrophic cardiomyopathy (HCM) has a varied clinical course due to its genotypic and phenotypic heterogeneity. Several autopsy studies have shown abnormalities of the mitral valve in some HCM patients. Cardiovascular magnetic resonance (CMR) has become the imaging modality...

Predictors of left atrial thrombus resolution in patients with mitral stenosis planned for percutaneous transvenous mitral commissurotomy(PTMC) See

Mitral stenosis (MS) is a common finding in Rheumatic Heart Disease (RHD). The current management of symptomatic mitral stenosis is Percutaneous Transvenous Mitral Commissurotomy (PTMC) unless it is contraindicated. The presence of Left Atrial Thrombus (LAT), however, is generally co...