Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum

Microfluidic devices for the detection of disease-specific proteins and other macromolecules, disease modelling and drug development: A review See

Microfluidics is a revolutionary technology that has promising applications in the biomedical field.Integrating microfluidic technology with the traditional assays unravels the innumerable possibilities for translational biomedical research. Microfluidics has the potential to build up a novel platform for ...

Contact Guidance Mediated by Hybrid Thread Topography Enhances Osseointegration of As-machined Ti6Al4V Dental Implant. See

Purpose The main objective of this study is to investigate the key role of as-machined implant design features on the osseointegration. The bone regeneration ability of the newly developed Ti6Al4V hybrid threaded tapered implant without any surface modification has been validated and&#...

Simultaneous synthesis of carbon quantum dots, fluorescent probes, biofilms and hydrochar from sustainable vermicompost for versatile applications See

Sustainable and renewable sources of nanomaterial synthesis are a demanding approach. This work provides new insight into the versatile applications of materials derived from vermicompost. The report explains the simultaneous conversion of vermicompost to hydrophilic and stable carbon quantum dots...

Fluorescent carbon dots tailored iron oxide nano hybrid system for in vivo optical imaging of liver fibrosis See

Hybrid nanoparticles are innovative invention of last decade designed to overcome limitations of single-component nanoparticles by introducing multiple functionalities through combining two or more different nanoparticles. In this study, we are reporting development of magneto-fluorescent hybrid nanoparticles b...

Multifunctional amino functionalized graphene quantum dots wrapped upconversion nanoparticles for photodynamic therapy and X-ray CT imaging. See

Herein, we designed and developed a multifunctional nanocomposites by complexing NaGdF4:Yb/Er nanoparticles (UCNPs) with amino functionalized graphene quantum dots (af-GQDs). In the as-prepared nanocomposite (af-GQD/UCNPs), properties of UCNPs and af-GQDs were incorporated into a single nanoplatform to...

Engineering of Tripeptide-Stabilized Gold Nanoclusters with Inherent Photosensitizing Property for Bioimaging and Photodynamic Therapy See

Gold nanoclusters have the characteristics of small size, unique optical properties, and eco-friendly synthesis that make them promising candidates for biomedical applications, especially for bioimaging. However, their inherent photochemical activity and therapeutic efficiency are largely unknown and remain...

Enriched adipose stem cell secretome as an effective therapeutic strategy for in vivo wound repair and angiogenesis. See

The therapeutic potential of adipose tissue-derived mesenchymal stem cells (ADMSCs) is well studied for use in non-healing wounds. However, concerns on the transplantable cell number requirement, cell expansion, cell viability, retained cell multipotency and the limited cell implantation time for ...

Blood brain barrier-on-a-chip to model neurological diseases See

The blood-brain barrier (BBB) is a vital and unique multi-dimensional selective barrier that helps maintain brain homeostasis. BBB is a complex and dynamic structure responsible for regulating the transport of ions and molecules. BBB contains several transporter proteins and tight junctions ...

A prospective cohort study on cerebrospinal fluid (CSF) diversion catheter-related infections in a tertiary referral neurosurgical care center (SCTIMST Project No 5410) See

Real-time classification of fnirs data to develop a brain computer interface using deep learning See

Machine learning classification of Alzheimer’s patients using SMRI volumetric data See

Simulation and Validation of FiO₂ Mechanism in Ventilator See

Functional connectivity within language regions in stroke patients with expressive aphasia during real-time functional magnetic resonance-based neurofeedback training See

Synthesis & characterization of stable iron oxide nanoparticles: potential for nucleic acid recovery See

Poly-L-Lysine modified Iron oxide nanoparticles : Synthesis, characterization and antimicrobial properties See

Development of fibro-porous polymeric membranes for WBC syringe filter by electrospinning See

In vitro characterization of collagen peptide incorporated fibrin sealant patches for wound healing applications See

Influence of the stiffness of carboxymethyl cellulose based hydrogels on the encapsulation efficiency of chondrocytes See

Physico chemical characterization of chitosan based scaffold as wound healing biomaterial See