Please use this identifier to cite or link to this item: http://dspace.sctimst.ac.in/jspui/handle/123456789/10002
Title: Lipoinsulin encapsulated alginate-chitosan capsules: intestinal delivery in diabetic rats
Authors: Ramadas, M
Paul, W
Dileep, KJ
Anitha, Y
Sharma, CP
Keywords: Chemistry; Engineering; Pharmacology & Pharmacy
Issue Date: 2000
Publisher: JOURNAL OF MICROENCAPSULATION
Citation: 17 ,4;405-411
Abstract: An oral formulation based on liposome encapsulated alginate-chitosan gel capsules was developed for insulin delivery for the treatment of diabetes. Liposome encapsulation helped to increase the encapsulation efficiency of insulin in alginate-chitosan capsules. This formulation delivers insulin in the neutral environment of the intestine, by-passing the acidic media in the stomach, with increased drug absorption and bioavailability. Oral administration of this formulation was found to reduce blood glucose levels when tested in diabetic rats.
URI: http://dspace.sctimst.ac.in/jspui/handle/123456789/10002
Appears in Collections:Journal Articles

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