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|Title:||Lipoinsulin encapsulated alginate-chitosan capsules: intestinal delivery in diabetic rats|
|Keywords:||Chemistry; Engineering; Pharmacology & Pharmacy|
|Publisher:||JOURNAL OF MICROENCAPSULATION|
|Abstract:||An oral formulation based on liposome encapsulated alginate-chitosan gel capsules was developed for insulin delivery for the treatment of diabetes. Liposome encapsulation helped to increase the encapsulation efficiency of insulin in alginate-chitosan capsules. This formulation delivers insulin in the neutral environment of the intestine, by-passing the acidic media in the stomach, with increased drug absorption and bioavailability. Oral administration of this formulation was found to reduce blood glucose levels when tested in diabetic rats.|
|Appears in Collections:||Journal Articles|
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