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|Title:||MODIFIED HYDROXYAPATITE MICROSPHERES AS IMMUNOADSORBENT FOR PLASMA PERFUSION - PRELIMINARY-STUDY|
|Publisher:||JOURNAL OF COLLOID AND INTERFACE SCIENCE|
|Abstract:||An improved solid-support, affinity immunoadsorbent suitable for extracorporeal perfusion of plasma is reported. This consists of hydroxyapatite microspheres coated with a thin layer of poly(vinyl alcohol) and immobilized phenylalanine as ligand. This adsorbent can remove IgG immunoglobulins specifically from plasma. The modified adsorbent may be used for direct hemoperfusion as a cheaper alternative to plasma adsorption therapy by eliminating cell separator for selective removal of antibodies belonging to immunoglobulin G class. (C) 1995 Academic Press, Inc.|
|Appears in Collections:||Journal Articles|
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