Please use this identifier to cite or link to this item:
|Title:||Plasma surface modification of fibroporous polycarbonate urethane membrane by polydimethyl siloxane: Structural characterization, mechanical properties, and in vitro cytocompatibility evaluation|
|Keywords:||Engineering; Materials Science|
|Publisher:||JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A|
|Abstract:||This article reports the surface modification of electrospun polycarbonate urethane membrane with polydimethyl siloxane (PDMS) using plasma-induced grafting technique for biomedical applications. The nonwoven membranes were characterized for their structure, performance, and compatibility with cells. The surface modification was confirmed by means of attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) and energy dispersive X-ray analysis (EDXA). ATR-FTIR and EDXA analyses displayed characteristic absorption peaks of PDMS for the membrane. The structure and morphology of the developed membranes were studied using scanning electron microscope and microcomputed tomography (mu CT). Scanning electron microscopy and mu CT revealed the fibrous morphology and percentage porosity of the membranes before and after plasma modification. Static mechanical tests showed that the tensile strength was greater than 8 MPa. Physical characterization of the membranes after immersion in hydrolytic and oxidative media supports their biostability. Cytotoxicity of the membrane was evaluated using L929 fibroblast cells, and the results indicated that the membrane is cytocompatible. Accordingly, these results highlight the potential of this fibrous membrane for biomedical applications. (c) 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 102A: 947-957, 2014.|
|Appears in Collections:||Journal Articles|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.