Please use this identifier to cite or link to this item: http://dspace.sctimst.ac.in/jspui/handle/123456789/10635
Title: Tropical endomyocardial fibrosis in India: a vanishing disease!
Authors: Vijayaraghavan, G
Sivasankaran, S
Keywords: Immunology; General & Internal Medicine; Research & Experimental Medicine
Issue Date: 2012
Publisher: INDIAN JOURNAL OF MEDICAL RESEARCH
Citation: 136 ,5;729-738
Abstract: Tropical endomyocardial fibrosis in India was a common medical problem in the coastal districts of south India, especially the Kerala State. The clinical and autopsy studies have shown left and right ventricular apical fibrosis, with varying degree of atrioventricular valve regurgitation. Left ventricular endomyocardial fibrosis presents with severe pulmonary hypertension and right ventricular endomyocardial fibrosis presents very high systemic venous pressure and congestive cardiac failure. Surgical management improved the natural history of the disease to some extent. Various infectious and toxic factors were postulated regarding its aetiology. During the last few years, incidence of the disease has decreased considerably. The only explanation identified is the significant improvement in the living standards of the people with the corresponding decline in the childhood malnutrition, infections, worm infestation and associated eosinophilia.
URI: http://dspace.sctimst.ac.in/jspui/handle/123456789/10635
Appears in Collections:Journal Articles

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