Please use this identifier to cite or link to this item: http://dspace.sctimst.ac.in/jspui/handle/123456789/10643
Title: ULTRASTRUCTURE OF ORAL SQUAMOUS-CELL CARCINOMA - A COMPARATIVE-ANALYSIS OF DIFFERENT HISTOLOGICAL TYPES
Authors: KANNAN, S
KARTHA, CC
CHANDRAN, GJ
PILLAI, MR
SUDHA, L
NALINAKUMARI, KR
NAIR, MK
BALARAM, P
Keywords: Oncology; Dentistry, Oral Surgery & Medicine
Issue Date: 1994
Publisher: ORAL ONCOLOGY-EUROPEAN JOURNAL OF CANCER PART B
Citation: 30B ,1;32-42
Abstract: Twenty-five oral carcinomas and five normal oral epithelial specimens were studied using light and electron microscopy. All histological types (well differentiated squamous cell carcinoma, moderately differentiated squamous cell carcinoma, poorly differentiated squamous cell carcinoma, verrucous carcinoma and spindle cell carcinoma) were seen in the study sample. In addition, 1 case of carcinoma in situ was also present. The normal oral epithelium consisted of three keratinising types (gingiva) and two non-keratinising types (buccal mucosa). The ultrastructural features of oral carcinomas showed good correlation with the features seen in light microscopy. The differentiation status of the lesions showed a relationship with cell and nuclear size, tonofilament and keratin content as well as few other cellular abnormalities. It was also observed that the fine details revealed by electron microscopy were often a means of explaining the characteristic histopathological features of oral carcinoma.
URI: http://dspace.sctimst.ac.in/jspui/handle/123456789/10643
Appears in Collections:Journal Articles

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