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Title: Varying clinical and imaging outcomes in patients with spontaneous thrombosis of vein of Galen malformation-a report of two cases
Authors: Jain, NK
Swaika, S
Thomas, B
Kesavadas, C
Kapilamoorthy, TR
Keywords: Neurosciences & Neurology; Pediatrics; Surgery
Issue Date: 2015
Citation: 31 ,5;809-813
Abstract: Vein of Galen malformations are rare congenital intracranial vascular malformations. The pathophysiological consequences usually manifest as high-output cardiac failure and neurological symptoms secondary to cerebral venous congestion and abnormal CSF flow. Management of these patients is complex. Indications and time to intervene are decided depending upon the age of child, clinical presentation, and multisystemic neonatal scores. Many of these children presenting early and who are not in cardiac failure are expectantly followed up. Spontaneous thrombosis of the vein of Galen malformation is a rare occurrence in these as such rare vascular malformations. This review reports two cases of spontaneous thrombosis of the vein of Galen malformations with varying clinical as well as imaging outcomes. Possible pathophysiologic mechanisms are discussed with review of literature. This report highlights the importance of vigilant clinical and imaging follow-up even after spontaneous thrombosis in the vein of Galen malformations.
URI: 10.1007/s00381-014-2612-3
Appears in Collections:Journal Articles

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