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Title: Medical Application of Engineered Nanoparticles
Authors: Reshma, VG
Krishnan, N
Mohanan, PV
Keywords: Nanoparticles; Safety; Medical Application; Bioimaging; Drug Delivery
Issue Date: Mar-2018
Publisher: EC Pharmacology and toxicolog
Citation: Reshma VG, Krishnan N, Mohanan PV. Medical Application of Engineered Nanoparticles. EC Pharmacology and toxicology. 2018;6(3):141-151
Abstract: Nanoparticles (NPs) are the particles that exist on a nanometer scale i.e. at least one dimension must be below 100 nm. Due to smaller size, they are highly reactive and show exceptional physical, chemical and optical properties compared to the bulk materials. These remarkable properties make them attractive candidate in various medical applications. Nowadays Nano medicine is a widely developing branch of science which deals with nanoparticle application in medical field. This review highlight the importance of engineered nanoparticles (ENPs) in various medical applications such as drug delivery, antimicrobial agents, photothermal therapy, magnetic hyperthermia, contrast agents in various imaging techniques and biosensors. Currently many NPs are under investigation for drug and gene delivery. Silver, quantum dots (QDs), nano-TiO2 etc. are used as biofilm therapeutic agents. ENPs like QDs act as theranostic agent i.e. they act as both diagnostic as well as therapeutic agent. ENPs have significant role in imaging techniques like MRI, CT scan etc. The risks related with the application of ENPs in various medical applications are not explored much and hence safety evaluation is mandatory before its clinical application.
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