Please use this identifier to cite or link to this item: http://dspace.sctimst.ac.in/jspui/handle/123456789/1246
Title: Ultrastructural evaluation of in vitro mineralized calcium phosphate phase on surface phosphorylated poly(hydroxy ethyl methacrylate-co-methyl methacrylate)
Authors: Sailaja, G. S.
Ramesh, P.
Varma, H. K.
Keywords: Biomaterials
Issue Date: 2010
Publisher: JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
Citation: JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE. 21; 4; 1183-1193
Abstract: The in vitro functionality of surface phosphorylated poly(hydroxy ethyl methacrylate-co-methyl methacrylate), poly(HEMA-co-MMA) to induce bioinspired mineralization of calcium phosphate phase is evaluated. The primary nucleation of calcium phosphate on the surface phosphorylated copolymer occurs within 3 days of immersion when immersed in 1.5x simulated body fluid and the degree of mineralization is proportional to the hydroxy ethyl methacrylate content in the copolymer. The calcium phosphate phase is identified as hydroxyapatite by X-Ray diffraction analysis. The transmission electron microscopic evaluation combined with selected area diffraction pattern and energy dispersive analysis exemplified that the primary nuclei of amorphous calcium phosphate transforms to crystalline needle like calcium rich apatite, within a period of 3 days immersion in simulated body fluid. The atomic force microscopic results corroborate the c-axis growth of the crystals within 3 days immersion in SBF.
URI: http://dx.doi.org/10.1007/s10856-010-3987-7
http://www.ncbi.nlm.nih.gov/pubmed/20099010
http://dspace.sctimst.ac.in/jspui/handle/123456789/1246
Appears in Collections:Journal Articles

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.