Please use this identifier to cite or link to this item: http://dspace.sctimst.ac.in/jspui/handle/123456789/237
Title: Changes in polyurethane calcification due to antibiotics
Authors: Chandy, T
Vasudev, SC
Sharma, CP
Keywords: Biocompatibility
Issue Date: 1996
Publisher: ARTIFICIAL ORGANS
Citation: ARTIFICIAL ORGANS. 20; 7; 752-760
Abstract: To develop artificial materials for prolonged use in the vascular system, the complicated process of surface-induced calcification must be better understood. Calcification was examined on porous polyurethane incubated in metastable solutions of calcium phosphate, and the role of certain antibiotics in the medium was evaluated. It seems that certain aminoglycoside antibiotics can modify polyurethane surfaces and, subsequently, their mineralization process. In addition, these antibiotics may alter the calcium transport through polyurethanes. Therefore, it is conceivable that certain antibiotics can, in addition to producing their antibacterial effect, modulate surface calcium binding by changing the calcium mobilization and crystallization. Additional studies are needed to develop applications.
URI: http://dx.doi.org/10.1111/j.1525-1594.1996.tb04536.x
http://dspace.sctimst.ac.in/jspui/handle/123456789/237
Appears in Collections:Journal Articles

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