Please use this identifier to cite or link to this item: http://dspace.sctimst.ac.in/jspui/handle/123456789/245
Title: Chemoprotective effect of Sobatum against cyclophosphamide toxicity in mice
Authors: Mohanan, PV
Devi, KS
Keywords: Toxicology
Issue Date: 1998
Publisher: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Citation: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 17; 2; 159-164
Abstract: The partially purified component of Solanum trilobatum named as Sobatum was found to be cytotoxic in Dalton's lymphoma ascites (DLA), Ehrlich ascites (EA) and tissue cultured cells. It significantly inhibited the peritoneal and solid tumours induced by DLA and EA tomour cells along with the chemically induced skin carcinogenesis. Sobatum did not produce any chromosomal anomalies in the bone marrow cells of Swiss mice. In the present study, we have evaluated the chemoprotective effect of Sobatum on cyclophosphamide induced toxicity in mice. The results showed that the co-administration of Sobatum increase the total leucocyte count, haemoglobin level, average life span of animals; we, concluded that Sobatum has chemoprotective action on cyclophosphamide induced toxicity.
URI: http://www.ncbi.nlm.nih.gov/pubmed/9700576
http://dspace.sctimst.ac.in/jspui/handle/123456789/245
Appears in Collections:Journal Articles

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.