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Title: Circulating immune complexes in cerebrospinal fluid of patients with tuberculous meningitis.
Authors: Mathai, A
Radhakrishnan, V V
Sehgal, S
Keywords: Immunology
Issue Date: 1991
Publisher: Indian journal of experimental biology
Citation: Indian journal of experimental biology. 29; 10; 973-6
Abstract: Circulating immune complexes (ICs) were isolated from cerebrospinal fluids (CSFs) of patients with tuberculous meningitis (TBM), non-tuberculous neurological diseases by a polyethylene glycol (PEG) precipitation method. Mycobacterium tuberculosis antigen 5 was detected in CICs of 30% patients with TBM, by sandwich ELISA. CIC level decreases during antituberculosis chemotherapy and therefore its detection can provide a method to monitor the therapeutic schedule in patients with TBM.
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