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Title: Clinical applications of susceptibility weighted MR imaging of the brain - a pictorial review
Authors: Thomas, Bejoy
Somasundaram, Sivaraman
Thamburaj, Krishnamoorthy
Kesavadas, Chandrasekharan
Gupta, Arun Kumar
Bodhey, Narendra K.
Kapilamoorthy, Tirur Raman
Keywords: Radiology
Issue Date: 2008
Citation: NEURORADIOLOGY. 50; 2; 105-116
Abstract: Introduction Susceptibility-weighted imaging (SWI) is a novel magnetic resonance (MR) technique that exploits the magnetic susceptibility differences of various tissues, such as blood, iron and calcification. This pictorial review covers many clinical conditions illustrating its usefulness.Methods SWI consists of using both magnitude and phase images from a high-resolution, three-dimensional fully velocity-compensated gradient echo sequence. Phase mask is created from the MR phase images, and multiplying these with the magnitude images increase the conspicuity of the smaller veins and other sources of susceptibility effects, which is depicted using minimal intensity projection (minIP).Results The phase images are useful in differentiating between diamagnetic and paramagnetic susceptibility effects of calcium and blood, respectively. This unique MR sequence will help in detecting occult low flow vascular lesions, calcification and cerebral microbleed in various pathologic conditions and aids in characterizing tumors and degenerative diseases of the brain. This sequence also can be used to visualize normal brain structures with conspicuity.Conclusion Susceptibility-weighted imaging is useful in differentiating and characterizing diverse brain pathologies.
Appears in Collections:Journal Articles

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