Please use this identifier to cite or link to this item: http://dspace.sctimst.ac.in/jspui/handle/123456789/2679
Title: Synthesis, characterization and electrospinning of calcium containing polyurethane urea
Authors: Nair, PA
Ramesh, P
Keywords: Biocompatibility;Calcium salt of p-aminobenzoic acid;Dynamic mechanical properties;Electrospinning;Polyurethanes
Issue Date: Nov-2015
Publisher: Advances in Polymer Technology
Citation: Nair PA , Ramesh P. Synthesis, characterization and electrospinning of calcium containing polyurethane urea. Advances in Polymer Technology. 2015.
Abstract: Calcium-containing segmented polyurethane urea was synthesized using a calcium salt of p-aminobenzoic acid, polytetramethylene glycol, and 4,4′-methylene bis(cyclohexyl isocyanate) and thereafter fabricated into three-dimensional scaffolds for the use in biomedical applications. Biocompatibility evaluation of the polymer showed that this newly developed metal-containing polyurethane urea demonstrated good cytocompatibility and hemocompatibility. The fabricating ability of the metal-containing polymer was studied by the electrospinning process. The effect of various parameters such as polymer concentration, applied voltage, and flow rate on the electrospinning process, morphology, and diameter of the resultant fibers was investigated. The findings indicate that increasing the concentration and flow rate of the solution increases the fiber diameter. It was also demonstrated that increasing the applied voltage decreases the fiber diameter. Mechanical property evaluation of the scaffolds showed that the strength of the scaffold depends on both the diameter and morphology of the fibers. As the fiber diameter increases from 1.6 to 3.02 μm, the tensile strength enhanced from 3 to 7 MPa.
URI: http://dx.doi.org/10.1002/adv.21559
http://dspace.sctimst.ac.in/jspui/handle/123456789/2679
Appears in Collections:Journal Articles

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