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Title: Post-irradiation "acquired cavernous angiomas" with drug resistant seizures
Authors: Menon, Ramshekhar N.
Baheti, Neeraj N.
Cherian, Ajith
Rathore, Chaturbhuj
Iyer, Rajesh S.
Radhakrishnan, Ashalatha
Keywords: Neurology
Issue Date: 2011
Citation: EPILEPSY RESEARCH. 96; 40910; 161-165
Abstract: Cavernomas are well-known congenital vascular lesions with presumably high epileptogenicity. We report two patients who developed cavernomas; both were in remission from childhood acute lymphoblastic leukemia following standard chemo-radiotherapy. They developed drug-resistant focal epilepsy secondary to cavernomas and were subjected to surgical/medical management. This report highlights the ictogenesis of radiation-induced "acquired" cavernous angiomatosis in the brain. Appropriate treatment, including resection of these lesions in selected cases, improves the quality of life in such patients. (C) 2011 Elsevier B.V. All rights reserved.
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