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Title: Biomimetic growth of calcium phosphate over ATP coupled PMMA films
Authors: Yokogawa, Y
Varman, HK
Sreenivasan, K
Keywords: Materials Science
Issue Date: 2003
Publisher: BIOCERAMICS 15
Citation: 240-2 ,;75-79
Abstract: Biomimetic growth of calcium phosphate phase was studied over phosphate group functionalised polymethy methaerylate (PMMA) films using Fourier Transform Infrared Spectroscopy (FTIR), Electron Spectroscopy (ESCA), Scanning Electron Microscopy (SEM) and Energy Dispersive X ray Analysis(EDS). PMMA films were prepared by dissolving PMMA pellets in chloroform and cast into thin sheets. The films were immersed in a methanol solution of sodium hydroxide before treating with 1.5% solution of adenosine triphosphate (ATP) at a pH of 5.2 for 24 hours. The films were then soaked in saturated lime solution for 4 days to initiate formation of calcium phosphate precursor phase over their surface. The above films immersed in simulated body fluid solution (1.5 x SBF) for more than 5 days led to the nucleation of apatitic calcium phosphate phase over the film surface.
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