Please use this identifier to cite or link to this item: http://dspace.sctimst.ac.in/jspui/handle/123456789/9584
Title: Differentiation of tubercular infection and metastasis presenting as ring enhancing lesion by diffusion and perfusion magnetic resonance imaging
Authors: Chatterjee, S
Saini, J
Kesavadas, C
Arvinda, HR
Jolappara, M
Gupta, AK
Keywords: Neurosciences & Neurology; Radiology, Nuclear Medicine & Medical Imaging
Issue Date: 2010
Publisher: JOURNAL OF NEURORADIOLOGY
Citation: 37 ,3;167-171
Abstract: Background and purpose. - As both tuberculoma and metastasis can manifest as solitary or multiple ring-enhancing intra-axial lesions that are difficult to differentiate by conventional magnetic resonance imaging (MRI), we hypothesized that the use of diffusion and perfusion MRI would make differentiation of these pathologies possible. Materials and methods. - Diffusion and T2*-weighted dynamic contrast-enhanced perfusion MRI scans from 11 patients with histologically proven tuberculoma or metastasis were retrospectively reviewed by two radiologists who were blinded to the pathology. All patients had a ring-enhancing lesion on conventional MRI. Apparent diffusion coefficient (ADC) values and regional cerebral blood volume (rCBV) were calculated from the walls of the lesions. Results. - Lesions showed different perfusion characteristics depending on whether they were due to tuberculosis or metastasis. The mean rCBV ratio between the lesion periphery and normal white matter was inferior to one for tubercular lesions and greater than five for metastases. However, ADC values were similar. Conclusion. - Measuring rCBV obtained by T2*-weighted dynamic contrast-enhanced perfusion MRI can help in differentiating intracranial tubercular mass lesions and metastases. (C) 2009 Elsevier Masson SAS. All rights reserved.
URI: 10.1016/j.neurad.2009.08.005
http://dspace.sctimst.ac.in/jspui/handle/123456789/9584
Appears in Collections:Journal Articles

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.