Interaction of molecularly imprinted polymers with creatinine

Abstract

Memory sites toward clinically relevant creatinine have been imparted in polymers based on methacrylic acid, AT-vinyl pyrrolidine, and 2-hydroxy ethyl methacrylate by the technique of molecular imprinting. The polymers are subjected to interaction with creatinine and creatine, a molecule of close resemblance with creatinine. The results show that selectivity is largely governed by the nature of the monomer. The reusability of the polymer is also demonstrated. (C) 1997 John Wiley & Sons, Inc.