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Title: Investigation of apoptotic events at molecular level induced by SERS guided targeted theranostic nanoprobe
Authors: Narayanan, N
Nair, LV
Karunakaran, V
Joseph, MM
Nair, JB
Ramya, AN
Jayasree, RS
Maiti, KK
Keywords: Chemistry; Science & Technology - Other Topics; Materials Science; Physics
Issue Date: 2016
Publisher: NANOSCALE
Citation: 8 ,22;11392-11397
Abstract: Herein, we have examined distinctive structural and functional variations of cellular components during apoptotic cell death induced by a targeted theranostic nanoprobe, MMP-SQ@GNR@LAH-DOX, which acted as a SERS "on/off" probe in the presence of a MMP protease and executed synergistic photothermal chemotherapy, as reflected by the SERS fingerprinting, corresponding to the phosphodiester backbone of DNA.
URI: 10.1039/c6nr03385g
Appears in Collections:Journal Articles

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