JOY, JKARTHA, CCBALAKRISHNAN, KG2012-12-042012-12-041993CARDIOLOGY. 82; 6; 409-414http://dx.doi.org/10.1159/000175895https://dspace.sctimst.ac.in/handle/123456789/1083Mitral valve (MV) specimens obtained at operation from 50 patients with ostium secundum atrial septal defect and associated MV dysfunction were studied macro- and microscopically to evaluate the structural lesions. The functional abnormalities in these patients were isolated mitral stenosis, isolated mitral regurgitation, mitral valve prolapse or mitral stenosis with regurgitation. Post-inflammatory lesions were commonly found in those with mitral stenosis who had a past history of rheumatic fever. Patients with mitral valve prolapse had either post-inflammatory lesions or lesions attributable to haemodynamic stress but different from the extensive lesions seen in floppy MV syndrome.Cardiology