Jayabalan, MLizymol, PPThomas, V2017-03-102017-03-10200049 ,1;88-9210.1002/(SICI)1097-0126(200001)49:1<88https://dspace.sctimst.ac.in/handle/123456789/10556Polyurethane-urea without ether linkages was synthesised using dicyclohexyl-methane diisocyanate (SMDI), hydroxy-terminated polybutadiene (HTPBD) and m-phenylenediamine (PDA). The hydrolytic stability of this polymer was investigated under in vitro conditions using Ringer's solution and phosphate-buffered saline, and the stability of candidate polyurethane-urea polymers was compared with that of polyurethane prepared with SMDI, HTPBD and I,4-butanediol [BD]. The change of tensile properties, hardness and surface properties in the aged polymer is significant for polyurethane when compared with those of polyurethane-urea polymer. The in vitro study revealed possible applications of polyurethane-urea for long-term biomedical applications. (C) 2000 Society of Chemical Industry.Polymer Science