Baldawa, Sachin SampatEaswer, Hariharan VenkatNair, SureshMenon, Girish2012-12-042012-12-042011NEUROSURGERY QUARTERLY. 21; 3; 214-218http://dx.doi.org/10.1097/WNQ.0b013e318215c8a5https://dspace.sctimst.ac.in/handle/123456789/740Virchow-Robin (VR) spaces are well-defined, normal pialined spaces along the walls of perforating arteries as they course in the brain parenchyma. These spaces are <2mm in size and are similar to cerebrospinal fluid (CSF) intensity on all pulse sequences. Dilated VR spaces are part of normal aging process. When VR spaces assume large bizarre, multicystic configuration, they are called as giant perivascular spaces and can be mistaken for other intracranial cystic space occupying lesions. When located in the mesencephalon-thalamic region, they produce acute hydrocephalus, which necessitates CSF diversion. We report a rare case of giant VR space in the mesencephalon-thalamic region causing symptoms related to obstruction of CSF flow due to aqueduct compression.Neurosurgery