RADHAKRISHNAN, VVMATHAI, A2012-12-042012-12-041991INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY. 29; 5; 437-440https://dspace.sctimst.ac.in/handle/123456789/895A simple dot-immunobinding assay (Dot-Iba) in nitrocellulose paper was developed for the detection of specific IgG antibody to Mycobacterium tuberculosis antigen 5 and mycobacterial antigen in cerebrospinal fluid of patients with tuberculous meningitis (TBM). The assay gave 77.1% sensitivity for the detection of IgG antibody to M. tuberculosis antigen 5 and 48.6% sensitivity for the detection of mycobacterial antigen in patients with TBM.ImmunologyPOTENTIAL APPLICATION OF DOT-IMMUNOBINDING ASSAY AS A RAPID DIAGNOSTIC-TEST IN TUBERCULOUS MENINGITIS