Sandhyamani, S2017-03-102017-03-101996,;467-470https://dspace.sctimst.ac.in/handle/123456789/10016Using low-protein tapioca-starch-based diets, degenerative cardiovascular changes similar to those in the human disorder, mucoid vasculopathy, were induced in a monkey model. The experiments were repeated using low-protein corn-starch-substituted diets and identical changes were obtained. The experiments demonstrated the etiologic role of protein deficiency in mucoid vasculopathy and lesion enhancement by either tapioca-starch or corn-starch in protein-deficient state. The experiments excluded the possibility of any toxic factors from tapioca starch in inducing the changes. The role of high carbohydrate (irrespective of the source) with low-protein intake in the development of degenerative diseases could also be established.Agriculture; Biotechnology & Applied Microbiology; Food Science & Technology