Hari, PRPaul, WSharma, CP2012-12-042012-12-042000JOURNAL OF BIOMEDICAL MATERIALS RESEARCH. 50; 2; 110-113http://dx.doi.org/10.1002/(SICI)1097-4636(200005)50:2<110https://dspace.sctimst.ac.in/handle/123456789/73Immobilized metal ion affinity chromatography (IMAC) is widely used. Transition metal ions have a high affinity to some peptide sequences. We have studied the selective adsorption of human IgG from a mixture of albumin, gamma-globulin, fibrinogen, and IgG onto Cu2+ ion-immobilized cellulose membrane. Although Cu2+ ligand is selective to IgG, in general gamma-globulins also are adsorbed. The simplicity and lower cost of Cu2+ ion-immobilized cellulose membranes may be useful for removing IgG from blood. (C) 2000 John Wiley & Sons, Inc.Biocompatibility