Browsing by Author "Hassan, Haseeb"

Now showing 1 - 4 of 4
  • Item
    Extraoccipital photoparoxysmal response in a case of focal encephalitis
    (EPILEPTIC DISORDERS, 2011)
    Photoparoxysmal response (PPR) is commonly associated with idiopathic generalised epilepsies. Most of the focal events induced by intermittent photic stimulation (IPS) are reported to be of occipital origin. Only six temporal lobe epilepsy patients have been reported in the literature with focal PPR at extraoccipital sites. We report a four-year-old girl with possible encephalitis who presented initially with epilepsia partialis continua of limbs on the right side. Interictally, she had left centro-parietal periodic lateralized epileptiform discharges (PLEDs). She responded to medical treatment and was free of seizures and motor and cognitive deficits at six months follow-up. Repeat EEG at follow-up showed left centro-parietal spikes accentuated by IPS. This is the first report of an extraoccipital, extratemporal focus showing PPR. The possible mechanism of PPR from this fronto-parietal epileptogenic focus is discussed.
  • Item
    Insights from a rare clinical presentation of herpes simplex encephalitis: adding to the catatonic dilemma?
    (The neurologist, 2011)
    BACKGROUND: Catatonia is associated with a variety of psychiatric and medical illnesses. Very little research is available on the syndrome and the exact neurobiological correlates are not known. Though various cortical and subcortical circuits are implicated in the pathogenesis, the role of cerebellum is unknown. We report an unusual presentation of herpes simplex encephalitis, clinically as catatonic stupor and radiologically as isolated symmetrical cerebellar involvement affecting the posterior cerebellum. We discuss the possible role of the cerebellum in producing a catatonic state.CASE REPORT: We describe the clinical presentation of catatonia in a 19-year-old woman with herpes simplex encephalitis. Her magnetic reasonance imaging showed features of viral cerebellitis involving the posterior cerebellum with hemorrhagic transformation. She lacked the classical frontotemporal involvement of herpes and recovered completely without physical or neuropsychological sequelae. She did not show signs associated with cerebellar disease at any point during the illness.CONCLUSIONS: This case provides compelling evidence for the possible role of the posterior cerebellum in the clinical presentation of catatonia. This is probably related to its role in controlling the nonmotor cerebral functions through corticocerebellar connections. Further studies of catatonic syndromes are needed to establish this association.
  • Item
    Structural correlates of fixation-off sensitivity: Evidences from a case of symptomatic occipital epilepsy with bilateral occipital gliosis
    (EPILEPSY RESEARCH, 2011)
    The fixation-off sensitivity (FOS), an epileptic phenomenon induced by elimination of central vision and fixation, is rarely seen in symptomatic occipital lobe epilepsy. The cerebral mechanisms and the structural correlate underlying FOS remain unclear. We describe a 19-year-old male with persistent left sided FOS following perinatal insult. MRI revealed asymmetric changes with more gliosis and ulegyria over the left posterior occipital cortex corresponding to the topographic representation of the macula. We suggest that the extensive denervation of the area representing macula along with the presence of hyperexitable ulegyric cortex is responsible for the phenomenon of FOS. (C) 2011 Elsevier B.V. All rights reserved.
  • Item