Browsing by Author "Jolappara, M."

Now showing 1 - 2 of 2
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    Atypical fungal granuloma of the sphenoid wing
    (JOURNAL OF NEURORADIOLOGY, 2009)
    A 29-year-old immunocompetent patient presented with a 3-month history of headache and vomiting. Computed tomography (CT) and conventional magnetic resonance imaging (MRI) revealed a mass lesion in the right sphenoid wing. The conventional imaging findings were typical of meningioma. However, diffusion-weighted imaging (DWI), susceptibility-weighted imaging (SWI) and perfusion-weighted imaging (PWI) all revealed details that were unusual for a meningioma. DWI showed diffusion blackout, perfusion was not raised in PWI, and susceptibility effects were noted in SWI. Based on these findings, the possibility of granuloma was kept as the differential diagnosis. Histopathological examination of the lesion was suggestive of fungal granuloma. This case report highlights the importance of advanced neuroimaging techniques in differentiating meningioma and granuloma. (C) 2009 Elsevier Masson SAS. All rights reserved.
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    Mean intensity curve on dynamic contrast-enhanced susceptibility-weighted perfusion MR imaging - review of a new parameter to differentiate intracranial tumors
    (JOURNAL OF NEURORADIOLOGY, 2011)
    Dynamic susceptibility contrast (DSC) perfusion imaging has been in clinical use for various indications, including characterization and grading of intracranial neoplasms. However, several technical factors can lead to pitfalls in image interpretation. This review discusses the extraction of T1 and T2* information from mean curve analysis of DSC perfusion imaging of various brain tumors, which provides further insights into tumor biology and, thus, may be useful in the differential diagnosis of such tumors. Indeed, by looking at the mean time signal intensity curve from the tumor bed in addition to the rCBV maps, it is possible to obtain further inferences of capillary density and lesion leakiness. When dynamic contrast enhanced (DCE) T1 perfusion is not available, DSC perfusion with mean curve analysis appears to be a valid alternative for characterizing various brain neoplasms in a routine clinical setting. (C) 2011 Elsevier Masson SAS. All rights reserved.