Browsing by Author "Joseph, E"

Now showing 1 - 3 of 3
  • Item
    Atypical meningioma: A clinicopathological analysis
    (NEUROLOGY INDIA, 2000) Joseph, E; Sandhyamani, S; Rao, MB; Nair, S; Radhakrishnan, VV
    In this retrospective study, 382 operated cases of meningiomas were reviewed, 32 cases (8.3%) were histopathologically classified as atypical meningioma, The anatomical locations and histological features in all the thirty-two cases were correlated with their recurrence rates and biological behaviour. The overall recurrence rate for atypical meningioma within two years was 28% as compared to 9.3% in benign meningiomas. It is being emphasized that an accurate histopathological interpretation of atypical meningioma is essential for predicting the recurrence, biological behavior as well as postoperative management modalities.
  • Item
    Fibrous dysplasia of the orbit in an infant
    (PEDIATRIC NEUROSURGERY, 2000) Joseph, E; Kachhara, R; Bhattacharya, RN; Radhakrishnan, VV; Balachandran, K
    Fibrous dysplasia is an idiopathic fibro-osseous lesion of the skeletal bones. These uncommon osseous lesions usually manifest within the first two decades of life. Its occurrence during infancy is extremely uncommon, and we describe here a case of fibrous dysplasia involving the orbit in a 9-month-old male child, Copyright (C) 2000 S. Karger AG. Basel.
  • Item
    Pathology of temporal lobe epilepsy: An analysis of 100 consecutive surgical specimens from patients with medically refractory epilepsy
    (NEUROLOGY INDIA, 1999) Radhakrishnan, VV; Rao, MB; Radhakrishnan, K; Thomas, SV; Nayak, DS; Santoshkumar, B; Joseph, E; Raghunath, B
    The neuropathological features of temporal lobe epilepsy were studied utilising 100 consecutive surgical specimens from patients with medically refractory complex partial seizures. A wide spectrum of neuropathological changes was recorded in 98 specimens. Fifty-eight specimens showed features of Ammon's horn sclerosis, Diffuse accumulation of corpora amylacea were demonstrated in the resected temporal lobes from 54 patients. Six patients had neoplastic lesions of temporal lobe. One unique case of dysembryoplastic neuroepithelial tumour showed a melanotic component within the tumour. The neuropathological features were regarded as nonspecific in 31% of cases. Our results indicate that a majority of patients with medically intractable epilepsy of temporal lobe origin reveal significant neuropathological features. Careful documentation of the neuropathological features and its correlation with radiological, electrophysiological and pre- and post-surgical clinical features will help in predicting the seizure outcome after temporal lobectomy for medically refractory epilepsy.