Browsing by Author "Kalliyana, KV"

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    Evaluation of Biomaterials Using Micro-Computerized Tomography
    (CT 2008: TOMOGRAPHY CONFLUENCE, 2008) Arun, TAT; Soumya, CKC; Saaj, US; Nair, MB; Kalliyana, KV
    Micro-computed tomography or Micro-CT is a high resolution, non-invasive, x-ray scanning technique that allows precise three-dimensional imaging and quantification of micro-architectural and structural parameters of objects. Tomographic reconstruction is based on a cone-beam convolution-back-projection algorithm. Micro-architectural and structural parameters such as porosity, Surface area to volume ratio, interconnectivity, pore size, wall thickness, anisotropy and cross-section area of biomaterials and bio-specimens such as trabecular bone, polymer scaffold, bio-ceramics and dental restorative were evaluated through imaging and computer aided manipulation of the object scan data sets.
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    Photopolymerized poly(2-hydroxyethyl methacrylate)/poly(epsilon-caprolactone)/poly(ethylene glycol) system as a potential wound dressing material
    (JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, 2015) Rethikala, PK; Kalliyana, KV
    Polymeric hydrogel systems based on poly(2-hydroxyethyl methacrylate), poly(epsilon-caprolactone), and poly(ethylene glycol) were prepared by photopolymerization using 2,4,6-trimethyl benzoyl diphenyl phosphine oxide as the photoinitiator. The structural details, morphology, and crystallinity were evaluated by Fourier transform infrared, scanning electron microscope, and X-ray diffraction analysis. The fluid uptake of the hydrogels was measured using swelling analysis. Based on a hemolysis assay, the prepared hydrogels were non-hemolytic. No attachment of fibroblasts to the hydrogel systems was observed. Stress-strain results indicated that the poly(2-hydroxyethyl methacrylate), poly(epsilon-caprolactone), and poly(ethylene glycol) hydrogel system (85:10:5) possessed better mechanical properties. Cytotoxic assessment by direct contact method of 85:10:5 systems found that the hydrogel was non-cytotoxic to L929 fibroblasts. This hydrophilic polymer system has a potential for wound dressing applications.