Browsing by Author "NAIR, RR"
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Item A SIMPLIFIED METHOD FOR CULTURE OF HUMAN-FETAL HEART-TISSUE(INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 1989) NAIR, RR; KARTHA, CCItem CELL-ADHESION AND GROWTH ON SYNTHETIC HYDROGEL BEADS(BULLETIN OF MATERIALS SCIENCE, 1989) SHIVAKUMAR, K; NAIR, RR; JAYAKRISHNAN, A; KARTHA, CC; VALIATHAN, MSItem CERIUM DEPRESSES PROTEIN-SYNTHESIS IN CULTURED CARDIAC MYOCYTES AND LUNG FIBROBLASTS(MOLECULAR AND CELLULAR BIOCHEMISTRY, 1991)The present study examined the effect of Cerium on protein synthesis in cultured cardiac myocytes and lung fibroblasts exposed to normal and markedly subnormal levels of Mg2+. Cerium was found to have a general inhibitory effect on protein synthesis in these cell types, including the synthesis of myofibrillar proteins in the cardiac myocytes. Further, the effect of the metal ion was more pronounced in cells exposed to the Mg2+ -deficient medium. The possible implications of the observations are discussed.Item DERMATOGLYPHIC STUDIES IN ENDOMYOCARDIAL FIBROSIS(INDIAN JOURNAL OF MEDICAL RESEARCH, 1987) NAIR, RR; BALAKRISHNAN, KGItem ENHANCED CERIUM CONCENTRATION IN MAGNESIUM-DEFICIENT PLANTS(CURRENT SCIENCE, 1989) NAIR, RR; GUPTA, PN; VALIATHAN, MS; KARTHA, CC; EAPEN, JT; NAIR, NGItem GEOCHEMICAL BASIS OF TROPICAL ENDOMYOCARDIAL FIBROSIS(CURRENT SCIENCE, 1995) EAPEN, JT; SHIVAKUMAR, K; NAIR, RR; KARTHA, CC; VALIATHAN, MSItem GEOCHEMICAL BASIS OF TROPICAL ENDOMYOCARDIAL FIBROSIS(CURRENT SCIENCE, 1994) VALIATHAN, MS; KARTHA, CC; NAIR, RR; SHIVAKUMAR, K; EAPEN, JTEndomyocardial fibrosis (EMF) has a marked preference for the tropics and the poor socio-economic class. Tropical soil is rich in minerals such as monazite and the endomyocardial samples of patients with EMF show higher levels of cerium - a major constituent of monazite - in combination with lower concentrations of magnesium. The geochemical hypothesis postulates that poor children are prose to develop magnesium deficiency because of insufficient intake and the higher growth needs for the element. The deficiency of magnesium promotes the absorption of cerium and enhances its toxicity which could form the basis for the initial injury in EMF.Item PARADOXICAL EFFECT OF CERIUM ON COLLAGEN-SYNTHESIS IN CARDIAC FIBROBLASTS(JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1992)Item SYNTHETIC HYDROGEL MICROSPHERES AS SUBSTRATA FOR CELL-ADHESION AND GROWTH(IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY, 1989) SHIVAKUMAR, K; NAIR, RR; JAYAKRISHNAN, A; THANOO, BC; KARTHA, CC