Browsing by Author "Nair, M D"

Now showing 1 - 6 of 6
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    Demonstration of Lafora bodies in a patient with myoclonus epilepsy.
    (The Journal of the Association of Physicians of India, 1996)
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    Inflammatory myopathies--a clinicopathologic study.
    (Indian journal of pathology & microbiology, 1997)
    In this study, clinical, histopathological and immunological profiles were analysed in ten patients with inflammatory myopathies. Polymyositis and dermatomyositis were more common than other forms of inflammatory myopathies. The pathogenetic mechanisms and distinguishing histopathological and immunological profiles between polymyositis and dermatomyositis have been highlighted.
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    Magnetic resonance imaging findings in a patient with sporadic motor neuron disease.
    (The Journal of the Association of Physicians of India, 1996)
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    Mitochondrial myopathies--a clinicopathological study.
    (Indian journal of pathology & microbiology, 1998)
    Mitochondrial myopathies are heterogeneous group of clinical disorders that can affect multiple systems besides skeletal muscles. The mitochondrial abnormalities in the skeletal muscles are morphologically identified by the presence of characteristic Ragged-red fibers (RRF) in the cryostat sections of the muscle stained with modified Gomori's trichrome stain. In this retrospective study, clinical and histopathological features in six patients with mitochondrial myopathies have been analysed. The utility of histochemical methods in confirming the diagnosis of mitochondrial myopathy has been emphasised.
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    Spinal muscular atrophy--a clinicopathologic analysis.
    (Indian journal of pediatrics, 1997)
    In this retrospective study the clinical features in 16 children with spinal muscular atrophy (SMA) were reviewed and classified into three stages. The muscle biopsy specimen were routinely processed with liquid-nitrogen-isopentane and 8 micron thick frozen-sections were studied for histochemical changes. The clinical features in Type III SMA resembled with limb-girdle muscular dystrophy and the muscle biopsy was useful in distinguishing these two entities. It is being evaluated that prenatal diagnosis of SMA is possible with DNA technology developed recently in our country.