Browsing by Author "Ramachandran, P"

Now showing 1 - 5 of 5
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    Changing the debate about health research for development
    (Journal of Public Health Policy, 2004) Abrahams, N; Adhikari, R; Bhagwat, IP; Christofides, N; Djibuti, M; Dyalchand, A; Gotsadze, G; Grzmava, O; Huertas, LL; Jacobs, T; Jewkes, R; Kapadia-Kundu, N; Karnikowski, MG; Kimboka, S; Kitua, AY; Lens, JU; Lopez, A; Lugina, H; Malecela-Lazaro; Mashalla, Y; Mishra, A; Mishra, SK; Mlay, R; Moreno, MJ; Mpanda, S; Mwanga, F; Ndossi, G; Nigenda, G; Nkwera, A; Nobrega, OT; Pahari, SK; Paz, SA; Phoolchareon, W; Ramachandran, P; Rannan-Eliya, RP; Rodrigues, KG; Salazar, A; Sarma, PS; Shija, J; Silver, LD; Tatsanavivat, P; Thankappan, KR; Tuesta, AJ; Vasadze, O; Velez, AC; Webster, N; Yesudian, CA
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    Emergency surgery after percutaneous transmitral commissurotomy: Operative versus echocardiographic findings, mechanisms of complications, and outcomes
    (JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2005)
    Objective: This study was undertaken to determine the clinical profile of patients undergoing emergency surgery after balloon mitral valvotomy, to note operative findings and compare them with those of transthoracic echocardiography, to describe the mechanisms of complications, and to describe outcomes.Methods: A retrospective study was undertaken of patients requiring emergency surgery after percutaneous mitral valvotomy with an Inoue balloon from January 1990 to December 2003. The data analyzed included demographic variables, causes and clinical presentations of complications, and outcome. In 14 consecutive cases of mitral regurgitation, an observational study comparing the operative findings with echocardiography was also undertaken.Results: In 1388 cases of valvotomy, complications necessitating urgent surgery occurred in 3 1 cases (2.2%). Acute mitral regurgitation occurred in 23 cases (74.2 %), and cardiac tamponade occurred in 8 cases (25.8%). Mitral regurgitation was due to leaflet tearing in all cases: anterior leaflet in 20 cases and posterior leaflet in 3 cases. Hypotension, orthopnea, and pulmonary edema were the clinical presentation for mitral regurgitation. Transthoracic echocardiography underestimated the severity of mitral valve pathology. Bilateral severe commissural fusion and pliable leaflet with paracommissural calcium was seen in anterior leaflet tearing. Cardiac tamponade with hemodynamic compromise occurred as a result of left atrial perforation in 6 cases, right atrial perforation in 1 case, and left ventricular perforation in 1 case. High septal puncture led to atrial perforation. Operative mortality was 9.6%, and low cardiac output developed in 29%.Conclusion: Acute mitral regurgitation and cardiac tamponade were the causes of emergency surgery after balloon valvotomy. Transthoracic echocardiolgraphy underestimated the severity of valve pathology.
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    Hutchinson-Gilford progeria syndrome with severe calcific aortic valve stenosis and calcific mitral valve
    (JOURNAL OF HEART VALVE DISEASE, 2004) Nair, K; Ramachandran, P; Krishnamoorthy, KM; Dora, S; Achuthan, TJ
    The case of a 12-year-old girl with clinical features of progeria with severe calcific valvar aortic stenosis is presented. The mitral valve showed the presence of calcium, and peripheral vascular disease was also present, though there was no family history of this. Aortic valve replacement was deferred because of insufficient data relating to this condition. The genetics and phenotypic mechanisms of the disease are reviewed. In view of the association of progeria with valve disease, all patients should undergo electrocardiography and echocardiography as part of their routine work-up.
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    Partial atrioventricular canal defect with cor triatriatum sinister: Report of three cases
    (JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2004)
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    Rebuttal: Percutaneous Valvuloplasty for Mitral Valve Restenosis
    (CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 2011) Nair, K; Sivadasanpillai, H; Sivasubramonium, P; Ramachandran, P; Tharakan, JA; Kumar, A; Sivasubramonian, S; Krishnamoorthy, KM; Dora, S