Browsing by Author "Rao, VRK"
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Item Endovascular treatment of carotido-cavernous fistula(RIVISTA DI NEURORADIOLOGIA, 2003) Gupta, AK; Rao, VRK; Kapilamoorthy, TR; Bhattacharya, RN; Joseph, S; Krishnamoorthy, TItem Evaluation, management, and long-term follow up of vein of Galen malformations(JOURNAL OF NEUROSURGERY, 2006) Gupta, AK; Rao, VRK; Varma, DR; Kapilamoorthy, TR; Kesavadas, C; Krishnamoorthy, T; Thomas, B; Bodhey, NK; Purkayastha, SObject. Vein of Galen malformations (VGMs) are extremely rare intracranial lesions. Clinical presentation and management strategies vary significantly in different areas of the world. The authors report their experience in evaluation, management, and long-term follow up of these lesions in India. Methods. Between October 1983 and June 2003, 25 patients with VGMs were referred to the authors' institution for evaluation and management. Ten children younger than 2 years of age presented with rapidly increasing head size as the chief complaint. Among 11 children 2 years of age or older, the most common presenting symptom was chronic headache. Four patients who presented during adulthood had chronic headache for many years before presentation. Angiographic evaluation of the lesion was performed in 21 patients. Fifteen patients were treated using endovascular techniques. Injection of the embolic material was performed after induction of systemic hypotension when the flow in the fistula was high. Complete occlusion of the arteriovenous shunt could be achieved in two patients with vein of Galen aneurysmal dilation (100% of patients with this type of malformation) and in five of the six patients with the mural type of malformation (83%). Among patients with the choroidal type of malformation, complete obliteration of the shunt could be achieved in three patients. In three patients with high-flow choroidal malformations, embolization carried out in a single sitting resulted in shunt reduction of nearly 90%. These patients received clinical follow up. Conclusions. The authors' experience in evaluation and management of VGMs reveals that in areas of the world where access to dedicated specialist care is limited, the clinical presentation of VGMs can differ appreciably from the classic descriptions in the literature. Endovascular management of these lesions results in excellent angiographic and clinical results.Item Experimental and Numerical Study of Stenotic Flows(JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS, 2016) Khader, SMA; Rajeev; Ayachit, A; Pai, R; Muraleedharan, CV; Zubair, M; Rao, VRKAtherosclerosis has been leading cause of deaths in several countries. Recent technical advances has allowed the investigation of stenotic flows and in understanding the implications with increased severity. Such studies shall provide detailed understanding of flow across stenosis and its progression. In the present study, a large artery representing segment of aorta is considered as test specimen. Experimental study is carried out by generating the pulsatile flow through pulsatile duplicator. Flow across normal and various severities of stenosis such as 25%, 50% and 75% are studied. Numerical simulation using CFD is also carried out in similar normal and stenosed models. A novel concept of using pulse duplicator to generate pulsatile waves and investigate the different stenosed models has been adopted. Results obtained experimentally and numerically are compared and agree well with that of clinical observations. This study demonstrates significant variation of haemodynamics in post-stenotic region with increased stenosis. Increased pulse pressure, phase lag is observed with increased severity. It is also observed that stenosis greater than 75% is significant as flow complexity is induced with considerable disturbance even in early and latter part of pulse cycle. Such study shall be useful in understanding the flow changes in stenosis and enhance clinical observation.Item Preoperative embolization of craniofacial vascular malformations(RIVISTA DI NEURORADIOLOGIA, 2003) Gupta, AK; Rao, VRK; Kapilamoorthy, TR; Joseph, S; Kesavadas, C; Bejoy, TItem Reversible non-enhancing lesions without focal neurological deficits in eclampsia(INDIAN JOURNAL OF MEDICAL RESEARCH, 1996)Nine patients with eclampsia, were subjected to computerized tomographic scan (CT scan) of the head to ascertain the changes in the brain that accompany seizures and encephalopathy of eclampsia, Only those patients who had a seizure within the past 24 h were included in this study, None of the patients had any focal neurological deficit. Six of the nine patients had abnormal findings on CT scan consisting of multiple non enhancing hypodensities in the cerebral white matter, One patient also had subependymal haemorrhage over the lateral ventricle. These changes were found to have disappeared when the CT scan was repeated on the seventh day, There was no correlation between the mean arterial blood pressure or the number of seizures and the presence of hypodensities in the brain, These findings suggest that subclinical changes in the form of reversible hypodensities and rarely bleeding can occur in eclampsia even when patients have no focal neurological deficits, It appears that these lesions represent focal areas of cerebral oedema, secondary to failure of autoregulation of cerebral blood flow.Item Spinal arteriovenous malformations - Role of interventional neuroradiology(RIVISTA DI NEURORADIOLOGIA, 2003) Gupta, AK; Rao, VRK; Bhattacharya, RN; Joseph, S; Kapilamoorthy, TR; Krishnamoorthy, TItem Vein of Galen malformations - An Indian experience(RIVISTA DI NEURORADIOLOGIA, 2003) Gupta, AK; Rao, VRK; Joseph, S; Kapilamoorthy, TR; Bejoy, B; Thomas, BB; Varma, DR