STRUCTURAL BASIS FOR MITRAL-VALVE DYSFUNCTION ASSOCIATED WITH OSTIUM-SECUNDUM ATRIAL SEPTAL-DEFECTS
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Date
1993
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Publisher
CARDIOLOGY
Abstract
Mitral valve (MV) specimens obtained at operation from 50 patients with ostium secundum atrial septal defect and associated MV dysfunction were studied macro- and microscopically to evaluate the structural lesions. The functional abnormalities in these patients were isolated mitral stenosis, isolated mitral regurgitation, mitral valve prolapse or mitral stenosis with regurgitation. Post-inflammatory lesions were commonly found in those with mitral stenosis who had a past history of rheumatic fever. Patients with mitral valve prolapse had either post-inflammatory lesions or lesions attributable to haemodynamic stress but different from the extensive lesions seen in floppy MV syndrome.
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Keywords
Cardiology
Citation
CARDIOLOGY. 82; 6; 409-414