Ischemic hyperintensities on T1-weighted magnetic resonance imaging of patients with stroke: New insights from susceptibility weighted imaging

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dc.contributorBaheti, Neeraj N.
dc.contributorCherian, Ajith
dc.contributorWattamwar, P. R.
dc.contributorKesavadas, Chandrasekharan
dc.contributorThomas, Bejoy
dc.date.accessioned2012-12-04T11:44:27Z
dc.date.available2012-12-04T11:44:27Z
dc.date.issued2010
dc.description.abstractHyperintensities on T1-weighted magnetic resonance imaging (MRI) in the setting of brain ischemia are usually considered hemorrhagic transformations. Such changes can also be seen due to "incomplete infarction" with selective neuronal loss. Arguments regarding the cause of these T1 hyperintensities have shuttled between gemistocytic astrocyte accumulation, tissue calcification and paramagnetic substance deposition. Susceptibility weighted imaging (SWI), a sensitive modality for detecting paramagnetic agents and blood products, has never been used to resolve this issue. The study was aimed to evaluate the SWI signal changes of T1 hyperintense lesion in stroke patients and understand its usefulness in differentiating a hemorrhagic infarct and an incomplete infarct. All the seven patients with infarct, having hyperintensities on T1 weighted MRI seen over the last one year were subjected to SWI. In none of the patients SWI failed to show any blooming. By doing SWI for T1-weighted hyperintensities, we can differentiate hemorrhagic infarct and a non-hemorrhagic "incomplete infarct". This differentiation will immensely help in planning management strategy and prognostication.
dc.identifier.citationNEUROLOGY INDIA. 58; 1; 90-94en_US
dc.identifier.urihttp://dx.doi.org/10.4103/0028-3886.60408
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/20228471
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/671
dc.publisherNEUROLOGY INDIA
dc.subjectRadiology
dc.titleIschemic hyperintensities on T1-weighted magnetic resonance imaging of patients with stroke: New insights from susceptibility weighted imaging
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