Carbon dot based non enzymatic approach for the detection and estimation of glucose in blood serum

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dc.contributor.authorKrishna, AS
dc.contributor.authorNair, PA
dc.contributor.authorRadhakumary, C
dc.contributor.authorSreenivasan, K
dc.date.accessioned2017-03-10T03:25:46Z
dc.date.available2017-03-10T03:25:46Z
dc.date.issued2016
dc.description.abstractIn this study we generated a simple, reliable and selective approach based on carbon dots (CDs) and 4-cyanophenylboronic acid (CPBA) for blood glucose sensing. The methodology relies on the quenching of the emission of CDs by CPBA followed by its recovery by glucose. The system consisting of CDs and CPBA was characterised by Fourier transform infra red spectrum, transmissions electron microscopic, dynamic light scattering instrument, UV-visible and fluorescence techniques. The response of the probe, CD-BA in presence of different concentrations of glucose was assessed. Linear range was obtained for glucose concentrations ranging from 1 to 30 mM. Interferences by other saccharides and various biomolecules coexisting in blood serum were negligible. The chemo sensor thus developed has been successfully used for the estimation of glucose in human blood serum. The system being sensitive, efficient and easy to perform is a promising platform for blood glucose sensing.
dc.identifier.citation3 ,5;-en_US
dc.identifier.uri10.1088/2053-1591/3/5/055001
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/9410
dc.publisherMATERIALS RESEARCH EXPRESS
dc.subjectMaterials Science
dc.titleCarbon dot based non enzymatic approach for the detection and estimation of glucose in blood serum
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