Structural correlates of fixation-off sensitivity: Evidences from a case of symptomatic occipital epilepsy with bilateral occipital gliosis

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dc.contributorHassan, Haseeb
dc.contributorJukkarwala, Anis
dc.contributorIyer, Rajesh Shankar
dc.date.accessioned2012-12-04T11:45:18Z
dc.date.available2012-12-04T11:45:18Z
dc.date.issued2011
dc.description.abstractThe fixation-off sensitivity (FOS), an epileptic phenomenon induced by elimination of central vision and fixation, is rarely seen in symptomatic occipital lobe epilepsy. The cerebral mechanisms and the structural correlate underlying FOS remain unclear. We describe a 19-year-old male with persistent left sided FOS following perinatal insult. MRI revealed asymmetric changes with more gliosis and ulegyria over the left posterior occipital cortex corresponding to the topographic representation of the macula. We suggest that the extensive denervation of the area representing macula along with the presence of hyperexitable ulegyric cortex is responsible for the phenomenon of FOS. (C) 2011 Elsevier B.V. All rights reserved.
dc.identifier.citationEPILEPSY RESEARCH. 94; 40910; 121-125en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.eplepsyres.2011.01.014
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/1085
dc.publisherEPILEPSY RESEARCH
dc.subjectNeurology
dc.titleStructural correlates of fixation-off sensitivity: Evidences from a case of symptomatic occipital epilepsy with bilateral occipital gliosis
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