Surgical Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease
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Date
2017-09
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Ann Indian Acad Neurol.
Abstract
The treatment of motor manifestations of Parkinson's disease (PD) is essentially a trade-off between adequate relief of motor symptoms and prevention and control of motor complications, particularly levodopa-induced dyskinesia (LID). Progression of PD is paralleled by a progressive difficulty in achieving the balance. Functional neurosurgical procedures provide sustained relief of LID in carefully selected patients when further tailoring of medical therapy fails to achieve this goal. Though deep brain stimulation (DBS) has superseded lesioning surgeries, pallidotomy still has a role in those patients in whom DBS is not feasible for financial or other reasons.
Description
Keywords
Deep brain stimulation; Parkinson's disease; levodopa-induced dyskinesia; pallidotomy
Citation
Krishnan S, Pisharady KK. Surgical Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease. Ann Indian Acad Neurol. 2017 JulSep;20(3):199-206.