Osteogenesis of a Bioactive Ceramic-Calcium Phosphosilicate Composite System in Goat Femur Defect
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Date
2011
Journal Title
Journal ISSN
Volume Title
Publisher
INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
Abstract
In spite of the array of synthetic bone grafts available, the pursuit for an ideal graft continues. In view of this, a synthetic bioactive calcium phosphosilicate composite (HABGS) has been developed combining the properties of hydroxyapatite and silicate system. The in vivo performance of HABGS granules in goat femur defect stimulated a favorable environment for de novo bone formation with faster resorption. The ceramic composite is attractive for its low Si content together with its negligible levels at implanted sites and vital organs postimplantation. Herein, we propose the safety and efficacy of this composite as a promising bone substitute.
Description
Keywords
Materials Science
Citation
8 ,3;491-500