Microstructured microspheres of hydroxyapatite bioceramic
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Date
2002
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
Abstract
Hydroxyapatite (HAP) particles having spherical geometry and 125-1000 mum in size range were prepared using a solid-in-water-in-oil (S/W/O) emulsion, cross-linking technique. An aqueous solution of chitosan containing different loading of HAP was dispersed as droplet in liquid paraffin using a stabilizing agent. Cross-linking of chitosan was induced by adding appropriate amount of glutaraldehyde saturated toluene. Chitosan microspheres containing HAP were sintered at 1150 degreesC to obtain pure HAP microspheres. The spheres thus produced were examined by scanning electron microscopy. The percentage yield and size distributions of the spheres were also determined. (C) 2002 KLuwer Academic Publishers.
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Keywords
Biomaterials
Citation
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE. 13; 7; 623-632