Baseline characteristics of participants in the Kerala Diabetes Prevention Programme: a cluster randomized controlled trial of lifestyle intervention in Asian Indians

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dc.contributor.authorSathish, T
dc.contributor.authorOldenburg, B
dc.contributor.authorTapp, RJ
dc.contributor.authorShaw, JE
dc.contributor.authorWolfe, R
dc.contributor.authorBalachandran, S
dc.contributor.authorD’Esposito, F
dc.contributor.authorAbsetz, P
dc.contributor.authorMathews, E
dc.contributor.authorZimmet, PZ
dc.contributor.authorThankappan, KR
dc.date.accessioned2016-08-06T07:25:12Z
dc.date.available2016-08-06T07:25:12Z
dc.date.issued2016-07
dc.description.abstractAims To describe the baseline characteristics of participants in the Kerala Diabetes Prevention Program. Methods The Kerala Diabetes Prevention Program is a cluster randomized controlled trial of lifestyle intervention for prevention of Type 2 diabetes mellitus in India. Participants in the study were those aged 30–60 years who had an Indian Diabetes Risk Score ≥ 60 and who were without Type 2 diabetes on oral glucose tolerance test. Data on demographic, lifestyle, clinical and biochemical characteristics were collected using standardized tools. Results A total of 2586 individuals were screened with the Indian Diabetes Risk Score, of these 1529 people (59.1%) had a score ≥ 60, of whom 1209 (79.1%) underwent an oral glucose tolerance test. A total of 202 individuals (16.7%) had undiagnosed Type 2 diabetes and were excluded, and the remaining 1007 individuals were enrolled in the trial (control arm, n = 507; intervention arm, n = 500). The mean participant age was 46.0 ± 7.5 years, and 47.2% were women. The mean Indian Diabetes Risk Score was 67.1 ± 8.4. More than two-thirds (69.0%) had prediabetes and 31.0% had normal glucose tolerance. The prevalence of cardiometabolic risk factors was high, including current tobacco use (34.4% in men), current alcohol use (39.3% in men), no leisure time exercise (98.0%), no daily intake of fruit and vegetables (78.7%), family history of diabetes (47.9%), overweight or obesity (68.5%), hypertension (22.3%) and dyslipidemia (85.4%). Conclusions The Kerala Diabetes Prevention Program recruited participants using a diabetes risk score. A large proportion of the participants had prediabetes and there were high rates of cardiometabolic risk factors. The trial will evaluate the effectiveness of lifestyle intervention in a population selected on the basis of a diabetes risk score.en_US
dc.identifier.citationSathish T, Oldenburg B, Tapp R J. Shaw J E, Wolfe R, Balachandran S, D’Esposito F,. Absetz P, Mathews E, Zimmet P Z , Thankappan. K R. Baseline characteristics of participants in the Kerala Diabetes Prevention Programme: a cluster randomized controlled trial of lifestyle intervention in Asian Indians. Diabetic Medicine. 2016.en_US
dc.identifier.urihttp://dx.doi.org/10.1111/dme.13165
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/2798
dc.publisherDiabetic Medicineen_US
dc.titleBaseline characteristics of participants in the Kerala Diabetes Prevention Programme: a cluster randomized controlled trial of lifestyle intervention in Asian Indiansen_US
dc.typeArticleen_US
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