Effect of nitrous oxide in reducing pain of propofol injection in adult patients
| dc.contributor | Sinha, PK | |
| dc.contributor | Neema, PK | |
| dc.contributor | Rathod, RC | |
| dc.date.accessioned | 2012-12-04T11:43:57Z | |
| dc.date.available | 2012-12-04T11:43:57Z | |
| dc.date.issued | 2005 | |
| dc.description.abstract | In a randomized, double-blind, prospective trial we compared the efficacy of pre-treatment with nitrous oxide (with or without premixed lignocaine in propofol) for the prevention of propofol-induced pain. Ninety consecutive patients were recruited in the study and divided into three groups of 30 each, who received either 50% nitrous oxide in oxygen along with lignocaine 40 mg mixed in 1% propofol 20 ml (Group NL), 50% nitrous oxide in oxygen without lignocaine in propofol (Group N), and 50% oxygen in air with lignocaine mixed in propofol 40 mg (Group L). Pain scores were graded on a four point verbal rating scale (0-3). Eighty-nine patients completed the study while one patient developed excitement, agitation and tremor during nitrous oxide in oxygen inhalation. Eleven patients (36.7%) complained of pain in the group L compared to 7 (23.3%), and 1 (3.3%), in groups N and NL respectively [group NL vs group L (P< 0.001) and group NL vs N (P< 0.001)]. There was no statistical difference observed between group N and group L. Inhalation of 50% nitrous oxide reduces pain on propofol injection. The combination of 50% nitrous oxide and lignocaine mixed with propofol was the most effective treatment. | |
| dc.identifier.citation | ANAESTHESIA AND INTENSIVE CARE. 33; 2; 235-238 | en_US |
| dc.identifier.uri | https://dspace.sctimst.ac.in/handle/123456789/416 | |
| dc.publisher | ANAESTHESIA AND INTENSIVE CARE | |
| dc.subject | Critical Care | |
| dc.title | Effect of nitrous oxide in reducing pain of propofol injection in adult patients |