POTENTIAL APPLICATION OF DOT-IMMUNOBINDING ASSAY AS A RAPID DIAGNOSTIC-TEST IN TUBERCULOUS MENINGITIS

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Date
1991
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Volume Title
Publisher
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY
Abstract
A simple dot-immunobinding assay (Dot-Iba) in nitrocellulose paper was developed for the detection of specific IgG antibody to Mycobacterium tuberculosis antigen 5 and mycobacterial antigen in cerebrospinal fluid of patients with tuberculous meningitis (TBM). The assay gave 77.1% sensitivity for the detection of IgG antibody to M. tuberculosis antigen 5 and 48.6% sensitivity for the detection of mycobacterial antigen in patients with TBM.
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Keywords
Immunology
Citation
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY. 29; 5; 437-440
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