Nano iron oxide-hydroxyapatite composite ceramics with enhanced radiopacity

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dc.contributor.authorAjeesh, M
dc.contributor.authorFrancis, BF
dc.contributor.authorAnnie, J
dc.contributor.authorVarma, PRH
dc.date.accessioned2017-03-10T03:27:41Z
dc.date.available2017-03-10T03:27:41Z
dc.date.issued2010
dc.description.abstractHydroxyapatite has been widely used for a variety of bone filling and augmentation applications. But the poorly resolved X-ray image of certain hydroxyapatite (HA) based implants such as porous blocks and self setting HA cements is a radiological problem to surgeons for monitoring of the implant and early diagnosis complications. In the present work the practical difficulty related to the reduced X-ray opacity was overcome by exploiting the contrast enhancement property of iron oxide nano particles. Sintered nano iron oxide-HA composite ceramics were prepared from powders produced through a co-precipitation route. The phase purity and bioactivity of the composites were analyzed as a function of percentage iron oxide in the composite. The X-ray attenuation of dense and porous composites was compared with pure HA using a C-arm X-ray imaging system and micro computed tomography. In all the prepared composites, HA retains its phase identity and high X-ray opacity as obtained for a composition containing 40 wt% iron oxide. The increased cell viability and cell adhesion nature depicted by the prepared composite offers considerable interest for the material in bone tissue engineering applications.
dc.identifier.citation21 ,5;1427-1434en_US
dc.identifier.uri10.1007/s10856-010-4005-9
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/10102
dc.publisherJOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
dc.subjectEngineering; Materials Science
dc.titleNano iron oxide-hydroxyapatite composite ceramics with enhanced radiopacity
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