Medical Application of Engineered Nanoparticles
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Date
2018-03
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EC Pharmacology and toxicolog
Abstract
Nanoparticles (NPs) are the particles that exist on a nanometer scale i.e. at least one dimension must be below 100 nm. Due to
smaller size, they are highly reactive and show exceptional physical, chemical and optical properties compared to the bulk materials.
These remarkable properties make them attractive candidate in various medical applications. Nowadays Nano medicine is a widely
developing branch of science which deals with nanoparticle application in medical field. This review highlight the importance of
engineered nanoparticles (ENPs) in various medical applications such as drug delivery, antimicrobial agents, photothermal therapy,
magnetic hyperthermia, contrast agents in various imaging techniques and biosensors. Currently many NPs are under investigation
for drug and gene delivery. Silver, quantum dots (QDs), nano-TiO2 etc. are used as biofilm therapeutic agents. ENPs like QDs act as
theranostic agent i.e. they act as both diagnostic as well as therapeutic agent. ENPs have significant role in imaging techniques like
MRI, CT scan etc. The risks related with the application of ENPs in various medical applications are not explored much and hence
safety evaluation is mandatory before its clinical application.
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Keywords
Nanoparticles; Safety; Medical Application; Bioimaging; Drug Delivery
Citation
Reshma VG, Krishnan N, Mohanan PV. Medical Application of Engineered Nanoparticles. EC Pharmacology and toxicology. 2018;6(3):141-151