Ultrastructural evaluation of in vitro mineralized calcium phosphate phase on surface phosphorylated poly(hydroxy ethyl methacrylate-co-methyl methacrylate)

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dc.contributorSailaja, G. S.
dc.contributorRamesh, P.
dc.contributorVarma, H. K.
dc.date.accessioned2012-12-04T11:45:38Z
dc.date.available2012-12-04T11:45:38Z
dc.date.issued2010
dc.description.abstractThe in vitro functionality of surface phosphorylated poly(hydroxy ethyl methacrylate-co-methyl methacrylate), poly(HEMA-co-MMA) to induce bioinspired mineralization of calcium phosphate phase is evaluated. The primary nucleation of calcium phosphate on the surface phosphorylated copolymer occurs within 3 days of immersion when immersed in 1.5x simulated body fluid and the degree of mineralization is proportional to the hydroxy ethyl methacrylate content in the copolymer. The calcium phosphate phase is identified as hydroxyapatite by X-Ray diffraction analysis. The transmission electron microscopic evaluation combined with selected area diffraction pattern and energy dispersive analysis exemplified that the primary nuclei of amorphous calcium phosphate transforms to crystalline needle like calcium rich apatite, within a period of 3 days immersion in simulated body fluid. The atomic force microscopic results corroborate the c-axis growth of the crystals within 3 days immersion in SBF.
dc.identifier.citationJOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE. 21; 4; 1183-1193en_US
dc.identifier.urihttp://dx.doi.org/10.1007/s10856-010-3987-7
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/pubmed/20099010
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/1246
dc.publisherJOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
dc.subjectBiomaterials
dc.titleUltrastructural evaluation of in vitro mineralized calcium phosphate phase on surface phosphorylated poly(hydroxy ethyl methacrylate-co-methyl methacrylate)
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