Polypropylene fumarate/phloroglucinol triglycidyl methacrylate blend for use as partially biodegradable orthopaedic cement
dc.contributor | Jayabalan, M | |
dc.contributor | Thomas, V | |
dc.contributor | Rajesh, PN | |
dc.date.accessioned | 2012-12-04T11:44:54Z | |
dc.date.available | 2012-12-04T11:44:54Z | |
dc.date.issued | 2001 | |
dc.description.abstract | Polypropylene fumarate/phloroglucinol triglycidyl methacrylate oligomeric blend-based bone cement was studied. Higher the percentage of phloroglucinol triglycidyl methacrylate, lesser the setting time. An optimum setting time could be arrived with 50: 50 blend composition of the two oligomers. Composite cement of 50:50 blend prepared with hydroxyapatite granules of particle size 125 mum binds bovine rib bones. The tensile strength of this adhesive bond was found to be 1.11 kPa. The thermal studies suggest the onset of cross-linking reaction in the cured blend if the blend is heated. The absence of softening endotherm in the cured blend shows the thermosetting-like amorphous nature of blend system, which may restrict the changes in creep properties. The in vitro biodegradation studies reveal possible association of calcium ions with negatively charged units of degrading polymer chain resulting in slow down of degradation. Relatively slow degradation was observed in Ringer's solution. The study reveals the potential use of polypropylene fumarate/phloroglucinol triglycidyl methacrylate as partially degradable polymeric cement for orthopaedic applications. (C) 2001 Elsevier Science Ltd. All rights reserved. | |
dc.identifier.citation | BIOMATERIALS. 22; 20; 2749-2757 | en_US |
dc.identifier.uri | http://dx.doi.org/10.1016/S0142-9612(01)00018-7 | |
dc.identifier.uri | https://dspace.sctimst.ac.in/handle/123456789/886 | |
dc.publisher | BIOMATERIALS | |
dc.subject | Biomaterials | |
dc.title | Polypropylene fumarate/phloroglucinol triglycidyl methacrylate blend for use as partially biodegradable orthopaedic cement |