Application of molecularly imprinted polymer as a drug retaining matrix

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dc.contributor.authorSreenivasan, K
dc.date.accessioned2017-03-10T03:25:33Z
dc.date.available2017-03-10T03:25:33Z
dc.date.issued1997
dc.description.abstractCopolymerization by gamma irradiation of 2-hydroxyethyl methacrylate with ethylene glycol dimethacrylate in the presence of hydrocortisone as model drug gave a molecular imprinted polymer (MIP). The hydrocortisone was removed from the matrix with chloroform and incorporated again from methanol solution. Release data show that 96% of the incorporated drug is retained after 30 days storage in a methanol/water (3:1 v/v) mixture. In comparison with hydrocortisone, only a small quantity of testosterone is absorbed by the matrix.
dc.identifier.citation246 ,;65-69en_US
dc.identifier.uri10.1002/apmc.1997.052460105
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/9319
dc.publisherANGEWANDTE MAKROMOLEKULARE CHEMIE
dc.subjectPolymer Science
dc.titleApplication of molecularly imprinted polymer as a drug retaining matrix
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