Studies on chemically crosslinkable carboxy terminated-poly(propylene fumarate-co-ethylene glycol)-acrylamide hydrogel as an injectable biomaterial.

dc.contributorKallukalam, B C
dc.contributorJayabalan, M
dc.contributorSankar, V
dc.date.accessioned2012-12-04T11:45:18Z
dc.date.available2012-12-04T11:45:18Z
dc.date.issued2009
dc.description.abstractCarboxy terminated-poly(propylene fumarate)-co-ethylene glycol) (CT-PPF-co-PEG) was prepared and set into crosslinked hydrogel material with acrylamide. The setting studies reveal that this copolymer system can be used as an injectable material. The hydrogel material exhibits a higher degree of swelling, good mechanical strength and flexibility. The hydrogel favours adhesion of L929 fibroblast cells without proliferation on the surface. However, cardiac fibroblast cells (isolated from new born rat (Wistar) hearts) adhere and proliferate on the hydrogel due to the formation of synergistic hydrophilic-hydrophobic surface-by-surface reorganization.
dc.identifier.citationBiomedical materials (Bristol, England). 4; 1; 15002-15002en_US
dc.identifier.urihttp://dx.doi.org/10.1088/1748-6041/25/1/015002
dc.identifier.urihttps://dspace.sctimst.ac.in/handle/123456789/1089
dc.publisherBiomedical materials (Bristol, England)
dc.subjectBiomaterials
dc.titleStudies on chemically crosslinkable carboxy terminated-poly(propylene fumarate-co-ethylene glycol)-acrylamide hydrogel as an injectable biomaterial.
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